What is SpotⓇ Ex?
Easier to Find | Expanded Indications | Exceedingly Cost Effective
Darker tattoo enables fast and easy identification1
- Tattooing has been shown to reduce OR time by up to 40 minutes 2

Guidelines recommend tattooing for follow-up procedures
Spot Ex is the only endoscopic tattoo indicated for clinical surveillance and surgical localization1.

- 1Spot Ex Indication. Instructions for Use. G45-006 Rev03. May 2018.
Find Lesions Fast at Follow-Up Procedures

Spot Ex is easier to find1 because it’s much darker than Spot2.
- 1Lee. P., Finding Endoscopic Tattoos: The Impact of Contrast. GI Supply. 2018
- 2Spot Ex Luminosity Lab Results. Northwestern Biological Imaging Facility. Nov 2017
Tattoos are Society Recommended

“Colonoscopic tattooing is performed to enable future identification, at colonoscopy or surgery, of malignant lesions (proven or suspected), polypectomy, EMR, or ESD sites, difficult-to-detect polyps, or dysplastic areas. All such lesions, other than those definitely located in the cecum, adjacent to the ileocecal valve, or in the low rectum, should be tattooed.”1
- 1Ferlitsch M, Moss A, Hassan C, et al. Colorectal polypectomy and endoscopic mucosal resection (EMR): ESGE Clinical Guideline. 2017.

Spot Ex is permanent1, enabling a lifetime of follow-up procedures.
In 121 follow-up exams of patients previously tattooed with Spot, 100% were visible – up to 11 years later.2
- 1Spot Ex Indication. Instructions for Use. G45-006 Rev03. May 2018.
- 2Jackson FW. Long-Term Visibility of Endoscopic Tattoos Using Sterile Carbon Suspension In A Prefilled Syringe. Am J Gastroenterol 2017; 112:S1–S45
Common Clinical Uses of Endoscopic Tattoos for Surgical Localization and Clinical Surveillance

Surgery
- Laparoscopic localization
- Faster surgeries1 with lower risk of wrong site resection2

Large Polyp
- Risk of unknown dysplasia <2mm from biopsy margin
- Referring to therapeutic endoscopist or surgery

EMR or ESD
- Piecemeal endoscopic mucosal resection (PEMR)
- Follow-up to monitor recurrence of residual

Difficult-to-Detect Polyps
- Sessile serrated adenomas
- Proximal side of folds
- Transverse colon with few landmarks
- 1Arteaga-Gonzalez I, et. al., The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors: a prospective comparative clinical study. World J Surg. 2006. 30(4):605–611.
- 2Acuna SA, et. al., Preoperative localization of colorectal cancer: a systematic review and meta-analysis. Surg. Endosc. 2017; 31:2366-2379.